Rora | RAR-related orphan receptor alpha

GeneMGI:104661Synonyms: Nr1f1, 9530021D13Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating alkaline phosphatase level	1 supporting dataset	Rora^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	6.05x10^-5
decreased startle reflex	1 supporting dataset	Rora^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	8.07x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Rora^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rora.

Associated images

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Histopathology

There is no histopathology data found for Rora.

IMPC related publications

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External links

No external links available for Rora.

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*Rora^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Rora^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rora^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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